ZD421

ZD421 Series Advanced Desktop Printers

A New Level of Ease of Use, Application Flexibility and Management

Elevate your expectations with the advanced desktop printer that delivers the features, flexibility, reliability and security you need – today and tomorrow. Featuring Zebra’s exclusive Print DNA software toolset, the ZD421 is easy to setup, operate, manage and maintain – onsite or remotely. Direct thermal, thermal transfer, healthcare and ribbon cartridge models support a wide variety of applications.

The ZD421 Series is Zebra's newest advanced desktop printer and includes standard and healthcare models (thermal transfer and direct thermal), as well as ribbon cartridge models (available in both the standard and healthcare models). The ZD421 will replace the GK420 and the ZD420. These legacy printers will reach end of life in Q4 2021.


The primary target markets include:

  • Retail
  • Healthcare
  • Transport & Logistics
  • Light Manufacturing

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